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Significance of a biopsy of genital warts Genital warts are a sexually transmitted disease

Genital warts are a sexually transmitted disease. Although in some people it does not sometimes cause a problem, in others it is the cause of cancer.


    1. What is genital warts? 

    Genital warts  are one of the most  common sexually transmitted diseases  . Nearly all sexually active people will be infected with at least one type of human papillomavirus (HPV), the virus that causes genital warts. This pathology can occur at any time, in any stage in the life of an adult. Genital warts tend to affect the moist tissues of the genital area. They may look like small bumps, flesh color or have a tiny, cauliflower-like appearance. In many cases, the warts are too small to see and are easily missed.

    Some genital virus strains can cause genital warts alone, while others can cause cancer. Vaccines can help protect against some genital HPV strains   provided the subject is vaccinated early in adolescence just before the risk factors are present.

    Genital warts in children are caused by the HPV 1-4 virus
    Genital warts is caused by the human papilloma virus - HPV


    Although most sexually active people can catch the genital virus at some point in their life and go away on their own, risk factors that can increase the risk of getting genital warts include the following:

    • Unsafe sex
    • Have sex with many partners
    • Get a  sexually  transmitted infection
    • Having sex with a partner who has a history of sexual problems without your own knowledge or without your own knowledge
    • Have sexual activity when you are a teenager
    • A  compromised immune system , such as HIV co-  infection  or immunosuppressant medication
    Indiscriminate sex
    Having sex with different people increases the risk of the disease

    2. What are the symptoms of genital warts?


    In women, genital warts can develop on the vulva, the vaginal wall, anus, the anal canal, and as far as the cervix. In men, lesions can occur in the head or trunk of the penis, scrotum or anus.

    Genital warts can also develop on the lining of the mouth, tongue, cheeks, tongue or throat of someone who has had oral sex with an infected person.

    In the presence of the above lesions and careful examination, the patient may have the following characteristics that are described below:

    • Small, flesh-colored, brown or pink bumps in the genital area
    • The appearance is like a cauliflower when the warts are close together
    • A feeling of itching or discomfort in the genital area
    • Causing bleeding during intercourse, rough contact
    • Sometimes genital warts can be so small and flat on the surface of the skin that they are invisible. However, it is rare to encounter genital warts that can multiply in large clusters even in a person with a pre-suppressed immune system.
    Image of male genital warts

    3. What is the role of genital warts biopsy?


    With the above skin lesions and the quality of sexual life affected, early diagnosis and early treatment of genital warts are of utmost importance.

    Among the diagnostic means, the significance  of genital warts biopsy  is most prominent. When the patient sees skin lesions appearing on the body with an itchy, easy-to-bleed sensation, they should be examined soon. If you observe that these lesions resemble genital warts, your doctor will confirm the diagnosis by performing a  biopsy of genital warts . Accordingly, a tissue from the lesion can be clamped and viewed under a microscope. For men, it  may be easier to perform a  biopsy of genital warts . In contrast for women, especially a lesion located in the vaginal wall or cervix, the  biopsy of genital warts  needs to be done at the same time as the  gynecological examination. on the specialized examination table and platypus.


    After taking a biopsy of genital warts , the specimens  will be preserved before being processed in the laboratory. Here, the tissue sample is stained and examined under a microscope to assess whether the damage is caused by human HPV. If the result is normal it means that no HPV-shaped cells can be found. In such cases, this lesion may be due to strains of an agent other than HPV and further confirmed by other specialized means if the lesion is atypical.

    If the specimen shows typical lesions caused by HPV, it is found to be positive. However, what anatomists need to be more aware of is the staging of HPV lesions. Specifically, in the early stages, the virus only causes chronic inflammatory damage. Some virulent strains of HPV can cause in-situ cell transformation into a true precancer or cancer stage. This is of particular importance in the  biopsy of  genital warts. From there, the patient is scheduled for appropriate treatment and monitoring.

    However, whatever the outcome is, it will only be available a few days after the procedure. Since these injuries can cause pain and bleeding, after a biopsy, sex should be avoided until the wound is completely healed.

    The specimen is examined under a microscope

    4. What are the complications of genital warts?


    If the patient does not see an early doctor or does not have  a biopsy of genital warts  to confirm the disease, the possible infectious complications from HPV are as follows:

    • Cancer:  Cervical cancer  is closely related to genital infections. Some types of HPV are also linked to  cancers of the vulva , anus, penis, and mouth and throat. That's why, while HPV infection doesn't always lead to cancer, it's important for women to get   regular Pap tests , as soon as there are no injuries, especially those who already have infection with higher risk types of HPV.
    • Problems during pregnancy: Although rare, during pregnancy the warts can expand, making it difficult to urinate. Warts on the vaginal wall can inhibit the elongation of vaginal tissues during childbirth causing often difficult labor. On the other hand, large warts on the vulva or in the vagina can cause bleeding when prolonged during and after birth.
    • Newborn warts: Some babies born to mothers with genital warts can develop warts in the throat. At this time, if the lesion is large, the child may need surgery to keep the airways from clogging.


    In summary,  genital warts biopsy  has important implications for the diagnosis and treatment of the disease. If detected as early, the disease is in an early stage, the patient is properly treated and can be completely cured. Conversely, any delay will make genital warts biopsy as cancer and the prognosis more difficult.

    Source: eupharmas